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The global distribution of permanent canine hypodontia: A systematic review

Korean Journal of Orthodontics 2021³â 51±Ç 1È£ p.55 ~ 74
Sivarajan Saritha, Mani Shani Ann, John Jacob, Fayed Mona M. Salah, ±¹À±¾Æ, Wey Mang Chek,
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 ( Sivarajan Saritha ) - University of Malaya Faculty of Dentistry Department of Paediatric Dentistry and Orthodontics
 ( Mani Shani Ann ) - University of Malaya Faculty of Dentistry Department of Paediatric Dentistry and Orthodontics
 ( John Jacob ) - University of Malaya Faculty of Dentistry Department of Restorative Dentistry
 ( Fayed Mona M. Salah ) - Cairo University Faculty of Dentistry Department of Orthodontics
±¹À±¾Æ ( Kook Yoon-Ah ) - Catholic University College of Medicine Department of Dentistry
 ( Wey Mang Chek ) - University of Malaya Faculty of Dentistry Department of Paediatric Dentistry and Orthodontics

Abstract


Objective: To systematically review studies on canine agenesis prevalence in different populations and continents, based on the jaw, sex, location, and associated dental anomalies.

Methods: Electronic and hand searches of English literature in PubMed, Web of Science, Scopus, OpenGrey, and Science Direct were conducted, and the authors were contacted when necessary. Observational studies (population-based, hospital/clinic-based, and cross-sectional) were included. For study appraisal and synthesis, duplicate selection was performed independently by two reviewers. Study quality was assessed using a modified Strengthening the Reporting of Observational Studies in Epidemiology checklist, with main outcome of prevalence of canine agenesis.

Results: The global population prevalence of canine agenesis was 0.30% (0.0?4.7%), highest in Asia (0.54%), followed by Africa (0.33%), and the least in Europe and South America (0.19% in both continents). Canine agenesis was more common in the maxilla (88.57%), followed by both maxilla and mandible (8.57%), and the least common was mandible-only presentation (2.86%). The condition was more common in females (female:male ratio = 1.23), except in Asia (female:male ratio = 0.88) and Africa (female:male ratio = 1). In Asia, unilateral agenesis was almost twice as prevalent as bilateral, but in Europe, the bilateral form was more common.

Conclusions: The overall prevalence of canine agenesis is 0.30%, with the highest prevalence in Asia, followed by Africa, Europe, and South America. The condition is more common in the maxilla than the mandible, and in females than males (except in Asia and Africa), with unilateral agenesis being more common in Asia and the bilateral form showing a greater prevalence in Europe.

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Canine agenesis; Prevalence; Continents

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KoreaMed